All You Need To Know About Weight-Loss Medications

2023-12-20

Kevin Hales

Standard weight-loss diets rarely work in the long run because they’re usually unsustainable and don’t address the root causes of weight gain. After all, you can only battle hunger pangs for so long before giving in to your cravings. That is where a variety of weight loss medications can help. 

Thanks to weight-loss medications like Semaglutide and Tirzepatide, you can finally achieve and maintain your results. Weight loss drugs like Semaglutide and Tirzepatide are appetite suppressants that can help you stick to your weight loss diet in the long run, ensuring consistent, sustainable results. This article explores your weight-loss medicine options so you can confidently take the first step toward your ideal weight.

What Is Weight-Loss Medication?

Weight-loss medications are pharmaceutical tools that aid in reducing weight and improving health outcomes. These medications typically work by suppressing appetite, increasing feelings of fullness, or reducing fat absorption. Available in various forms like weight loss pills, weight loss injections, and lozenges, these drugs are often prescribed to individuals who struggle with weight-related health issues and have not found success with diet and exercise alone. They are most effective when used in conjunction with lifestyle changes, including a balanced diet and regular physical activity.

 

Picture of compounded semaglutide from ShedRx
Compounded Smeaglutide is just as effective at a fraction of the cost

Types of Weight Loss Medications

Semaglutide

Semaglutide is a GLP-1 receptor agonist primarily used for weight management. It mimics a hormone that targets areas of the brain involved in appetite regulation, leading to reduced hunger and calorie intake. Initially developed for diabetes management, its effectiveness in weight loss has gained significant attention. Semaglutide is administered through injections and, more recently, in lozenge form by ShedRx, offering an alternative for those who prefer a needle-free option. Its use typically accompanies lifestyle changes for optimal results.

Tirzepatide

Tirzepatide is a newer class of weight-loss drugs that combines the actions of GLP-1 and GIP receptor agonists. This dual mechanism enhances its effectiveness in reducing appetite and controlling blood sugar levels, making it a potent tool for weight management. Typically administered through weekly injections, Tirzepatide has shown significant results in weight reduction, particularly for individuals with obesity or weight-related health issues. It’s often part of a comprehensive weight loss plan that includes dietary and lifestyle modifications.

The Semaglutide Boom

Semaglutide was initially developed as a medication for the treatment of type-2 diabetes. It can regulate blood sugar levels, which helps with diabetes management. Developed by Novo Nordisk, it received FDA approval in 2017 under the brand name Ozempic. However, individuals who underwent the treatment identified a curious side effect of the weight loss medicine: they were no longer hungry. Soon, its potential in weight management was realized.

Semaglutide’s popularity skyrocketed when clinical studies revealed its effectiveness in substantial weight loss. Individuals who took Semaglutide weight loss injections found that they no longer suffered from food cravings or the hunger pangs that often derailed their weight loss efforts. This led to its widespread acceptance among healthcare providers and those seeking weight loss solutions. Semaglutide is now one of the most popular weight loss medications on the market.

The Tirzepatide Revelation

Tirzepatide is a relatively new player in the weight loss medication arena, but it has quickly gained recognition for its unique dual-action mechanism. Developed by Eli Lilly and Company, Tirzepatide combines the effects of GLP-1 and GIP receptor agonists, enhancing its efficacy in weight loss and blood sugar control. Initially developed for diabetes treatment, its notable impact on weight loss has led to broader applications in obesity and weight management.

The emergence of Tirzepatide has been met with enthusiasm in the medical community and among those seeking effective weight loss solutions. The compound’s ability to significantly reduce body weight and improve metabolic health marks it as a game-changer in the field. Furthermore, Tirzepatide’s dual-pronged approach to weight management makes it even more effective than Semaglutide, making it suitable for those seeking significant weight loss.

Semaglutide vs. Tirzepatide for Weight Loss

Semaglutide and Tirzepatide are currently the two leading weight loss drugs. Both have shown promising results but differ in their mechanisms, applications, and results. We offer a comparative analysis of Semaglutide and Tirzepatide, evaluating their effectiveness, modes of action, and suitability for different individuals seeking weight loss.

 

semaglutide can also treat diabetes
Semaglutide helps curb appetite and improve insulin sensitivity

Mechanism of Action

Semaglutide promotes weight loss through its action as a GLP-1 receptor agonist. GLP-1, a hormone produced in the gut, is key in regulating appetite and food intake. By mimicking GLP-1, Semaglutide enhances feelings of fullness and satiety, leading to reduced caloric intake. It also slows gastric emptying, prolonging the sensation of fullness after meals. Additionally, Semaglutide improves insulin sensitivity, which can aid in weight management.

Tirzepatide aids in weight loss by combining the effects of GLP-1 and GIP receptor agonists. This dual action suppresses appetite and boosts energy expenditure. The GLP-1 component decreases hunger and caloric intake, similar to Semaglutide, while the GIP aspect further enhances metabolic health and weight loss. Tirzepatide’s ability to control blood sugar levels is also crucial in its effectiveness, making it a potent option for those seeking weight loss.

The Results

Semaglutide shows weight loss results typically within a few weeks of starting treatment. Patients may experience varying degrees of weight reduction, depending on individual factors such as diet, exercise, and adherence to the medication regimen. In a clinical setting, patients typically experience a weight loss of about 5.9% after 3 months and around 10.9% after 6 months of treatment. Furthermore, patients lost about 12-15% of body weight over 68 weeks.

Tirzepatide users often see initial weight loss results within the first few weeks of treatment. The amount of weight loss can vary, but studies show that Tirzepatide can lead to an average weight loss of 20% of the initial weight over 68 weeks. Since Tirzepatide combines the actions of GLP-1 and GIP receptors, it curbs appetite and enhances metabolism. Consequently, Tirzepatide can lead to more substantial weight loss in the long run.

How to Self-Administer Weight Loss Injections:

  • Gather the necessary items: an injection pen, needles, alcohol wipes, and a sharps container.
  • Wash your hands thoroughly with soap and water for cleanliness.
  • Check the medication label and expiration date before each use.
  • Cleanse the chosen injection site (abdomen, thigh, or upper arm) with an alcohol wipe.
  • Attach a new needle to the injection pen following the manufacturer’s instructions.
  • Remove air bubbles from the pen by holding it upright and tapping gently.
  • Set the correct dose on the injection pen.
  • Pinch a fold of skin at the injection site.
  • Insert the needle into the pinched skin at a 90-degree angle.
  • Press the injection button to administer the medication.
  • Count slowly to 10 to ensure the full dose is delivered.
  • Withdraw the needle and safely dispose of it in a sharps container.
  • Rotate injection sites with each dose to prevent skin irritation.

It’s important to strictly adhere to the prescribed dose schedule and not self-adjust the dose. Consult our ShedRx healthcare professionals regularly to adjust your plan as needed and follow the guidelines for the safety and effectiveness of the treatment​​​​.

Can You Also Get Weight Loss Pills or Lozenges?

Yes, in addition to injections, weight loss medications are available in pill and lozenge forms. ShedRx offers appetite suppressants like Semaglutide as lozenges, offering a needle-free alternative to patients who might be concerned about needle usage. Lozenges dissolve slowly in the mouth, providing the same benefits as Semaglutide weight loss injections. If you’re concerned about weight loss injections and would rather use weight loss pills or lozenges, please consult your ShedRx healthcare provider to explore your options.

 

woman playing pickleball after using semaglutide
Being active is a key pice to a healthy lifestyle.

Weight Loss Diet vs. Weight Loss Medication

A weight loss diet typically involves modifying food intake to create a caloric deficit, either by eating less, choosing lower-calorie foods, or both. Diets may emphasize whole grains, lean proteins, fruits, and vegetables while limiting sugars and fats. The effectiveness of a diet often hinges on adherence and lifestyle changes. While weight loss diets can be effective in the short term, adhering to a calorie-deficit diet for extended periods is incredibly difficult, and most individuals eventually relapse.

Weight loss medications, on the other hand, offer a clinical approach to aid those who struggle with diet and exercise alone. These medications, such as Semaglutide and Tirzepatide, work by suppressing appetite, increasing feelings of fullness, or reducing the absorption of fats. Weight loss drugs don’t work independently — they simply curb your appetite and boost metabolism, thus allowing you to get the most out of your weight loss diet.

To achieve and sustain your ideal weight, you can’t choose between weight loss diets or weight loss medications. You need both. Weight loss diets facilitate significant weight loss; weight loss drugs allow you to stick to your calorie-deficit diet for extended periods. The two work hand-in-hand to help you lose weight and keep it off.

 

semaglutide vial

The Next Step: Schedule Your Virtual Consultation

Embarking on your weight loss journey can be both exciting and overwhelming. The first step towards a healthier you is scheduling a virtual consultation with our ShedRx healthcare provider. This initial meeting is key to understanding your unique needs and goals. During the consultation, our healthcare professionals assess your health history, discuss your weight loss objectives, and explore suitable medication options, like Semaglutide or Tirzepatide, alongside lifestyle changes.

Following the consultation, you’ll have a clearer roadmap for your weight loss journey, including guidance on diet, exercise, and the appropriate use of weight loss medications. This is a critical step in ensuring your weight loss journey is safe, effective, and sustainable.

 

Semaglutide helps to curb appetite and gain control over cravings to aid weight loss.

Kevin Hales

Related Topics

Shed is fully committed to supporting your weight-loss journey. We continue to offer a range of effective weight-loss medications and are excited to launch alternative options to help you reach your goals. Here’s how Shed is managing the FDA’s recent communication regarding access to Compounded Semaglutide Injections:

What’s Happening with Compounded Semaglutide?

As of today, your medication subscription, including dosage and pricing, will remain unchanged for at minimum the next 90 days. This is happening, because the FDA recently updated the status of semaglutide on the shortage list as “resolved.” Comparable to the removal of tirzepatide from the shortage list, there is currently legal action against the FDA. We anticipate that semaglutide will continue to be available while this legal action takes place.

Your Treatment Options

We understand how important your health is and are here to help you transition smoothly to other proven weight-loss medications in the meantime. Here are other weight-loss medication options:

  • Injectable Compounded Tirzepatide: Similar to semaglutide, compounded tirzepatide will provide you with similar benefits and results with an easy, once-weekly injection.
  • Semaglutide Liquid Drops: Enjoy the benefits of GLP-1 medication without needles, thanks to our compounded oral semaglutide.
  • Tirzepatide Liquid Drops: Enjoy the benefits of tirzepatide without needles, thanks to our compounded oral tirzepatide. These will continue to be available indefinitely and are a great alternative to injectable tirzepatide.
  • Name-Brand Medications: We now offer name-brand medications including Mounjaro®, Wegovy®, and Ozempic®.

As always, we promote a holistic approach to weight loss in order to better encourage long-lasting wellness. This means incorporating healthy nutritional, physical, mental, and sleep habits to nurture a lifetime of longevity. These habits, taught and supported in our available Health Coaching program, in conjunction with weight-loss medication, can aid those looking to reach their health goals.

Liquid Semaglutide Drops provide an easy, convenient way to take weight-loss medication without needles.
Liquid Semaglutide Drops provide an easy, convenient way to take weight-loss medication without needles.

How to Switch Your Treatment

Please note you do not need to transition from your compounded semaglutide injections today. We do encourage you to consider what your preference will be. Switching is simple and we’re here to help every step of the way. There are two simple ways to go about this:

  • Schedule a follow-up visit with a licensed provider from your Patient Portal. Navigate to the “Schedule” tab along the top menu and book a time to discuss a program change.
  • Reach out to the Care Team by emailing support@shedrx.com or texting them at 833-658-7433 to request a program change.

FAQs:

Why is semaglutide being phased out?

The FDA has updated guidelines which impact the availability of compounded semaglutide. All companies that currently offer compounded semaglutide are being required to phase out the availability of the drug to their consumers.

Will I still get results with other options?

Yes! You may anticipate similar results with alternative options.

How long do I have to make the switch?

We would encourage you to explore our alternative medication options within the next 2-3 months to ensure the continuity of your care.

Meet Shed Protein’s lighter, fruitier protein option. This new supplement offers a refreshing alternative to our chocolate Shed Protein. It’s a two-in-one powder which provides low-calorie protein to support muscle and electrolytes to boost energy, all while hydrating in a flavorful way.

What’s is Shed Clear Protein Made Up Of?

  • Clear Whey Protein Isolate: This is an extremely purified version of whey protein and helps with maintaining muscle, as well as repairing and growing it.
  • Sodium: By managing water, sodium balances fluid and hydration.
  • Potassium: Potassium encourages balance of electrolytes and well-functioning muscles in order to evade muscle fatigue, dehydration, and bloating.
  • Magnesium: This assists in producing energy and relaxing muscles to help with metabolism, muscle fuel, and to avoid cramps.

Why is Shed Clear Protein Important?

As shown, Shed Clear Protein is made up of these specific ingredients to support you in specific ways. These include:

  • Electrolyte balance and hydration
  • Build and maintain muscle
  • Aid metabolism, satiety, and weight loss
  • Energy support
Clear Protein is the answer to a refreshing, energizing protein supplement, now live through ShedRx.
Clear Protein is the answer to a refreshing, energizing protein supplement, now live through ShedRx.

Why Does Shed Clear Protein Support a GLP-1 Medication Journey?

Easily-Digestible Formula:

Clear Whey protein isolate, a highly bioavailable form of protein, is easier to digest and, with the benefit of added electrolytes, helps hydrate on a cellular level, optimizing the breakdown of nutrients more effectively.

Promotes Protein Intake and Hydration for Satiety and Recovery:

Clear Whey protein isolate supports muscle repair and growth. Combined with electrolytes to help restore sodium, potassium, and magnesium balance, this mix is ideal for post-exercise recovery or daily needs, delivering a dual benefit for optimal performance.

Convenient Way to Get Protein and Stay Hydrated:

Convenient grab-and-go packets are designed to support your nutritional needs between meals or as a quick boost during the day. Shed Clear Protein encourages water intake with three refreshing flavors, making hydration enjoyable, nourishing, and satisfying.

How to Use Shed Clear Protein

Add 1 packet to a bottle, shaker cup, or glass and shake or stir well to mix. Wait to let the foam settle and enjoy anytime. Shed Clear Protein provides a lighter protein option when appetite is low. It’s a great snack between meals to boost protein intake and sustain energy levels. It also provides a way to hydrate during or after a workout for muscle repair and electrolyte replacement.

Try It Out

See for yourself how Shed Clear Protein can impact how you feel in your health and wellness journey. Head here to grab yours now!

The start of a new year is the perfect time to set fresh health and wellness goals. For many, this includes tackling weight loss, which can often feel overwhelming without the right tools and support. At ShedRx, we understand that the journey to better health is unique for everyone, which is why we’ve developed a range of premium supplements designed to make the process easier, more effective, and sustainable.

Whether you’re looking to boost energy, curb cravings, or support your metabolism, our products are here to help you stay motivated and on track every step of the way. To get a snapshot of Shed Supplements, read over this info to learn how they can be a powerful ally in helping you achieve your weight-loss goals this upcoming year and beyond.

GLP-1 Revive

What It Is: With GLP-1 Revive, you’ll get targeted relief for nausea, digestion, and reflux along with metabolism and energy support, allowing you to stay focused and comfortable while on a GLP-1

What’s In It:

  • Vitamins and minerals—Active forms of Vitamin B12, folate, and CoQ10 support energy levels, while chromium picolinate aids in metabolism and may contribute to fat loss.
  • Digestive enzymes—Papain, bromelain, and protease break down protein, while cellulase helps digest fiber. Together, they support digestion, enhance nutrient absorption, and reduce digestive discomfort.
  • Herbs—Ginger root, chamomille, and lemon balm extract aid in relieving indigestion, bloating, gas, and nausea, common side effects of a GLP-1 medication.
  • Propbiotic—Sporevia is a patented probiotic backed by science that supports overall digestive health. This is done by supporting healthy gut bacteria in the gut microbiome, reducing digestive upset.
  • Adaptogenic
mushrooms—Reishi, Lion’s Mane, and Cordyceps help support stress, metabolic repair, and energy levels. They’re rich in beta-glucans to support gut health.

What It Does:

  • Nausea, reflux, gas, and bloating relief
  • Metabolism, weight-loss, and body composition support
  • Enhanced nutrient absorption and replenishment
  • Energy support and help in combating fatigue
  • Digestion support and overall gut health

GLP-1 Boost

What It Is: Through craving control and reduced appetite, GLP-1 Boost provides an alternative to injections, while still reaching your weight-loss goals.

What’s In It:

  • Vitamin B12—Essential for energy production and a well-functioning metabolism in its bioavailable form
  • Eriomin—A lemon-flavonoid antioxidant which encourages GLP-1 production and supports insulin sensitivity, inflammation, and gut health
  • Berberine—Comes from Berberis aristata plant bark and helps enhance glucose metabolism and GLP-1 levels for better blood sugar control and reduced cravings
  • Capsaicin—The active compound in chili peppers, boosts metabolism, curbs appetite and supports fat burning

What It Does:

  • Metabolism support
  • Craving control
  • Blood glucose support
  • Appetite control
Shed Supplements are a great resource to replenish your body, especially while taking weight-loss medications, when vital nutrients can be lacking.
Shed Supplements are a great resource to replenish your body, especially while taking weight-loss medications, when vital nutrients can be lacking.

Shed Protein

What It Is: This advanced 100% whey protein isolate offers a rich, decadent chocolate flavor, crafted to deliver high-quality protein to support muscle growth and recovery.

What’s In It:

  • 22 g protein—Supports muscle preservation and satiety
  • 2 g fat—Provides essential fatty acids for overall health
  • 2 g—Helps regulate blood sugar levels without excessive calorie
  • 110 calories—Offers a low-calorie option for weight-conscious individuals

What It Does:

  • Muscle preservation
  • Satiety and cravings control
  • Metabolic boost
  • Blood sugar stability

Smoothie Greens

What It Is: GLP-1 medications can make it harder to get enough fiber, leading to constipation and bloating. Smoothie Greens provide fiber to help regulate your digestive system.

What’s In It:

  • Spirulina—Offers antioxidant and anti-inflammatory properties
  • Wheat grass—Boosts immunity and enhances energy levels
  • Ginger pander—aids in digestion and reduces nausea

What It Does:

  • Supports metabolism and digestion
  • Helps digestion
  • Naturally increases energy levels
  • Fills nutritional gaps
Shed Supplements are a great resource to replenish your body, especially while taking weight-loss medications, when vital nutrients can be lacking.
Shed Supplements are a great resource to replenish your body, especially while taking weight-loss medications, when vital nutrients can be lacking.

Shed Collagen Peptides

What It Is: This is essential for maintaining a healthy level of collagen in the body. Collagen is one of the most abundant proteins in the body and is responsible for keeping the skin, hair, and nails healthy.

What’s In It:

  • Glycine
  • Proline
  • Hydroxyproline
  • Alanine

What It Does:

  • Skin health
  • Hair health
  • Nails health

Magnesium Glycinate

What It Is: Magnesium Glycinate benefits the body by reducing cellular stress, which in turn can help support normal blood pressure, sleep, and support overall wellbeing.

What’s In It:

  • Mineral magnesium—helps to be more bioavailable and gentle on the stomach
  • Glycine, an amino acid—helps to be more bioavailable and gentle on the stomach

What It Does:

  • Sleep support
  • Calms nerves
  • Bone health
  • Manages blood pressure
  • Helps with muscle relaxation, cramping, and spasms

No matter where you are at in your wellness journey, it’s always important to make sure you’re getting the proper support your body needs to function at its finest. To check out Shed Supplements and discover how they can benefit you in your health journey, whether on a GLP-1 medication or not, click here.

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