8 Do’s And Don’ts While On Semaglutide Or Tirzepatide

2023-11-01

Kevin Hales

Whether new to Semaglutide and Tirzepatide or multiple months in, you may wonder what to eat or drink, how to reach weight-loss goals more quickly, how to avoid negative side effects or what lifestyle changes will keep the weight off. According to ShedRx providers Dr. John Bernard and Dr. Vinson Di Santo, as well as general recommendations for a healthy lifestyle, here are eight tips and suggestions to help in your weight-loss journey:

Movement

Woman flexing while on semaglutide
Dr. Bernard encourages patients to listen to their body in regards to exercise while on Semaglutide or Tirzepatide.

1. Exercise

Whether fond of exercise or not, it will assist in weight-loss. Resistance-training will help to maintain muscle and focus more on shedding fat. Therefore, this will also help tone your body more.

Stay active, Bernard suggested. However, avoid drastic change in workouts. He advised that patients stick with what they were doing prior to taking medication rather than to undergo a new, vigorous exercise regimen. You don’t want to burn yourself out.

Di Santo said, “Engage in activities that you can do for 10 or 20 years without struggle.” He encouraged clients to participate in exercise that they enjoy to remain engaged more long-term.

Insider said that according to personal trainer Luke Worthington, “The aim when losing weight should be to change your body composition — the ratio of fat to muscle — not just become a smaller ‘skinny fat’ version of yourself.”

Muscle uses calories at rest. It is an active tissue, which means that strengthening muscles will help maintain weight loss. Eating a high-protein diet will allow muscles to grow and become stronger which helps to lose fat rather than losing weight, in general.

While he did note that the best approach to exercise is including both cardio and weight training, Bernard emphasized the idea of staying with what they did before. “The key is, really, to just follow what your body’s telling you.”

Nutrition

2. Protein

Not only will protein-rich foods keep you fuller longer, but they will also assist in maintaining muscle. Shoot for protein to make up ¼ of your meals and choose leaner options such as chicken, turkey, fish, tofu and beans as much as possible.

Bernard taught a general rule to go by is to consume one gram of protein for each kilogram a person weighs on a daily basis. For example, if an individual weighs 180 pounds, roughly 81 kilograms, the suggestion is to consume about 81 grams of protein daily.

While each individual varies, he said this is a good goal to shoot for, as an increase of protein has seemed to help patients. He encouraged those on medication to swap out red meats for leaner options, such as chicken and fish.

3. Fruits and vegetables

Fruits and vegetables will add fiber to your diet, as well as vitamins and minerals. They help to maintain blood sugar, as well. When sitting down to eat, double check if half of the plate is filled with fruits and vegetables. If not, maybe add a few. “You want to stay focused on things like vegetables and whole grains, especially,” Bernard stated.

Di Santo expressed the value in eating a balanced diet. “A good structure would be a typical way we once ate in more ancient times,” he said. “Eat the way our great grandparents ate before they had bad options.” He explained this means eliminating low-value foods which are unnecessary.

woman looking at flowers on semaglutide.
Dr. Di Santo advises Semaglutide and Tirzepatide users to focus on a balanced diet.

4. Whole grains

The last ¼ of the plate should be filled up with whole grains. They are rich in fiber and nutrients and allow for greater satiety. Some suggestions include whole wheat bread and pasta, brown rice, oats or quinoa.

5. Water

It is stressed that water consumption is imperative in order to maintain hydration and limit potential side effects, swapping out sugary drinks for good, old-fashioned H2O. The University of Missouri System suggests that individuals should drink roughly half of their body weight in ounces each day and even more if exercising.

“Very often, people are substituting water with a different type of beverage that dehydrates them more,” Di Santo said. He encouraged individuals to drink water when thirsty over a sweet drink or energy drink.

Nutrition to Avoid

6. High-fat foods

Stay away from anything greasy or fried which may cause an upset stomach or digestive issues. When including fats in a daily diet, seek out healthy fats and do so sensibly. Examples of healthy fats are: seeds, nuts, avocados and coconut oil.

Bernard counseled against food items that are processed or high in saturated fats. He added that high-fat foods, including butter, whole milk and red meat should also be consumed in moderation.

7. Added sugar

While it may show up unexpectedly, whether in sauces, dressings or frozen meals, watch out for added sugars so as not to spike blood sugar or worsen symptoms. It may work against the weight-loss medication, doing the exact opposite of the desired purpose of Semaglutide and Tirzepatide.

Bernard added that sweets, like candy, cookies, cakes, pies, etc. are not very nutritious. They have a high amount of sugar and carbohydrate content.

8. Alcohol

Alcohol consumption may worsen possible side effects of Semaglutide and Tirzepatide. Bernard said it is full of “empty calories.” Semaglutide and Tirzepatide slow the digestion process, so limiting alcohol consumption will lessen the possibility of gastrointestinal distress symptoms.

In conclusion

UCLA Health stated, “When used in conjunction with diet and exercise, [Semaglutide] can cause significant weight loss.” In other words, while Semaglutide and Tirzepatide, alone, are effective in losing weight, they are not as influential as paying attention to how you are fueling and strengthening the body.

By intaking proteins, fruits, vegetables, whole grains and water, and limiting high-fats, added-sugars and alcohol, this will be a catalyst to weight-loss. In addition, incorporating strength training to target different muscle groups will ensure quickened results.

Bernard said most people on medication do not see any side effects at all and if they do, the influence is minimal and may be controlled through changes in diet. Generally, excellent results are produced, meaning a great deal of weight has come off and, therefore, the patient feels better physically and emotionally about themselves.

“Most people really do [obtain] pretty good success,” Bernard said. “And a lot of people — it really changes their life too, and improves their overall health and certainly their emotional sense of well-being.”

Bernard noted that while the perfect medication for weight-loss does not exist, Semaglutide and Tirzepatide are as close as they come.

“They are definitely the best we’ve ever had and they really are game-changing treatments for weight-loss for a condition that, in the past, has been very difficult to manage and treat,” Bernard said. “We are certainly seeing a lot of success with these medications.”

Semaglutide helps to curb appetite and gain control over cravings to aid weight loss.

Kevin Hales

Related Topics

We are fully committed to supporting your weight-loss journey and we’re looking forward to offering a range of effective alternative options to help you reach your goals. Here’s how we are managing the FDA’s recent communication and how you can transition to these other effective and affordable options.

What’s Happening with Tirzepatide?

The FDA has issued a letter on the availability of compounded tirzepatide injections. As a result, compounded tirzepatide injections will soon no longer be available. ShedRx has always been aware of this outcome and has been vigorously preparing alternative programs and medications to ensure a smooth transition for you.

We will continue to offer compounded tirzepatide injections through March 19, 2025 and are here to help you transition smoothly to other proven weight-loss medications in the meantime.

Your Treatment Options

We understand how important your health is. To ease the transition, we are offering 20% off your first month of Tirzepatide Liquid Drops if you switch to this option! This is an oral administration of tirzepatide and is an effective alternative to help you along your weight-loss journey. Additionally, here are other your other options as you transition off of tirzepatide injections:

  • Injectable Compounded Semaglutide: Similar to tirzepatide, compounded semaglutide will provide you with similar benefits and results with an easy, once-weekly injection. 
  • Semaglutide Liquid Drops: Enjoy the benefits of GLP-1 medication without needles, thanks to our compounded oral semaglutide.
  • Tirzepatide Liquid Drops: Enjoy the benefits of tirzepatide without needles, thanks to our compounded oral tirzepatide. These will continue to be available indefinitely and are a great alternative to injectable tirzepatide.
  • Brand Name Medications: We will soon offer brand name medications such as Mounjaro, Wegovy, Ozempic, and Rybelsus.
Semaglutide Liquid Drops and Tirzepatide Liquid Drops just dropped! They provide and easy, convenient way to take weight-loss medication without needles.
Semaglutide Liquid Drops and Tirzepatide Liquid Drops just dropped! They provide and easy, convenient way to take weight-loss medication without needles.
Semaglutide Liquid Drops and Tirzepatide Liquid Drops just dropped! They provide and easy, convenient way to take weight-loss medication without needles.
Semaglutide Liquid Drops and Tirzepatide Liquid Drops just dropped! They provide and easy, convenient way to take weight-loss medication without needles.

How to Switch Your Treatment

Please note you do not need to transition from your tirzepatide injections today. We do encourage you to consider what your preference will be. Switching is simple and we’re here to help every step of the way. There are two simple ways to go about this:

  • Schedule a follow-up visit with a licensed provider from your Patient Portal. Navigate to the “Schedule” tab along the top menu and book a time to discuss a program change, OR
  • Reach out to the Care Team by emailing support@shedrx.com or texting them at 833-658-7433 to request a program change.

FAQs:

Why is tirzepatide being phased out?

The FDA has updated guidelines which impact the availability of compounded tirzepatide. All companies that currently offer compounded tirzepatide are being required to phase out the availability of the drug to their consumers.

Will I still get results with other options?

Yes! Tirzepatide Liquid Drops are compounded using SubMagna™. This ensures that tirzepatide retains its efficacy when compounded in this liquid vehicle.

How long do I have to make the switch?

We will continue to offer compounded tirzepatide injections until March 19, 2025. Leading up to that date, you will be prompted by our team to make a decision about what your preferred new method of treatment will be following March 19.

Hi, I’m Beth! I’m a certified health coach and group personal trainer with over a decade of experience. I specialize in nutrition and have carved out a unique niche in medical weight loss, creating tailored, effective plans that deliver real results. My approach focuses not only on achieving short-term goals, but also on building lasting health and longevity for my clients. My expertise and strategic guidance provide a clear, sustainable path to a healthier life. I hope the following will help you to do just that!

Beth, a ShedRx health coach
Beth, a ShedRx health coach

The holidays are a time of joy and celebration, but they can also bring extra demands on our time and energy. With the busy social events, festive meals, and family gatherings, it’s natural for routines to be tested. If you’re on a GLP-1 weight-loss journey, it can feel especially challenging to prioritize workouts, healthy meals, and consistency with your goals. The fun of the season combined with the allure of delicious holiday treats may make it feel like staying on track requires extra effort. 

Here’s the good news: With a little planning and creativity, you don’t have to let the holiday bustle throw you off course. It’s absolutely possible to embrace the holidays while staying aligned with your goals. Here are some tips to help you enjoy the season without compromising your progress:

1. Incorporate Movement Throughout the Day

You don’t need to carve out hours at the gym each day to stay active during the holidays. Try splitting up your movement—morning stretches, a walk at lunch, and some light yoga in the evening can do wonders. Even if you’re on a tight schedule, simple steps like taking the stairs instead of the elevator can add up quickly. Movement is about consistency, not duration, so make it a habit that fits naturally into your day.

Quick Tip: Set a timer every couple of hours to remind yourself to take a 5-minute break and move your body, whether it’s a quick walk or some light stretching!

2. Meal Prep Like a Pro

Holiday meals and treats can quickly throw off your healthy eating, but a little preparation can make all the difference. Dedicate some time each week to prepare your meals so healthy options are always within arm’s reach. Stock up on grab-and-go snacks like chopped veggies, boiled eggs, or protein shakes to resist temptation when hunger strikes. When nutritious food is ready to grab, you’re less likely to fall into the trap of unhealthy choices.

Quick Tip: Block off an hour on Sundays to batch-cook your meals and snacks and organize them in individual containers. That way, you can enjoy nutritious meals without scrambling during the week!

3. Prioritize Protein

Feeling full and satisfied makes it easier to avoid overindulging in holiday sweets. Make protein a priority in every meal and snack which helps maintain stable blood sugar levels and keeps cravings in check. Whether it’s a turkey lettuce wrap, a protein shake, or a grilled chicken salad, protein should take center stage in your holiday meals to help you feel satisfied and energized throughout the day.

Quick Tip: Pack a handful of protein-rich snacks like roasted chickpeas or a protein bar in your bag to keep hunger at bay and stay on track.

4. Create Small Rituals to Stay Grounded

Even in the excitement of the holidays, creating small rituals can help you stay focused on your goals. Whether it’s a 5-minute morning meditation or an evening stretching routine, these rituals serve as reminders of what’s important. Even a few minutes of mindful breathing or stretching can reset your energy, making it easier to stay on track with your wellness goals.

Quick Tip: Set a daily alarm for a 3-minute “wellness break” to give your mind and body the attention it needs.

You don’t have to let the holiday business ruin your progress. It’s totally possible to celebrate while staying on track with your goals.
You don’t have to let the holiday business ruin your progress. It’s totally possible to celebrate while staying on track with your goals.

5. Hydrate with Purpose

Holiday beverages like hot chocolate, eggnog, and festive cocktails can sneak extra calories and sugar into your diet. Make sure you’re staying hydrated by drinking plenty of water throughout the day. Alternating between your holiday drinks and water will help balance out the extra sugar and keep your energy steady. Hydration is key to maintaining focus, reducing cravings, and supporting overall wellness.

Quick Tip: Carry a reusable water bottle with you everywhere you go and drink a full glass of water before indulging in any holiday beverages.

6. Get Creative with Healthier Versions of Treats

Indulging in holiday treats doesn’t mean you have to derail your progress. There are plenty of healthy alternatives that can satisfy your sweet tooth. Try baking cookies with almond flour or using natural sweeteners like stevia or monk fruit for a lower-carb dessert. Look for ways to make your favorite holiday treats work for your health goals, without feeling deprived.

Quick Tip: Make your holiday desserts using ingredients like almond flour or coconut flour to create delicious, lower-carb alternatives that taste just as festive!

7. Stay Engaged with Your Support Circle

Having a support system during the holidays is a game changer. Connect with a friend, family member, or health coach who understands your health journey. Whether it’s through text messages, social media check-ins, or meal-sharing ideas, staying connected will keep you motivated to stay on track, even when things get busy.

Quick Tip: Schedule weekly check-ins with your accountability buddy to share victories and challenges, keeping the holiday joy front and center.

8. Practice Self-Compassion

The holidays are meant to be a time of joy, not perfection. There will be moments when things don’t go as planned, whether it’s skipping a workout or indulging in an extra cookie. Instead of feeling guilty, remember your journey is about progress, not perfection. Embrace the holidays with grace and focus on getting back on track with your next meal or movement.

Quick Tip: If you miss a workout or indulge a little too much, don’t stress. Get back to your healthy habits with your next meal. Balance, not perfection, is key!

The holiday season is all about balance and celebrating the memories you make. With small, intentional choices, you can enjoy everything this season has to offer while staying connected to your goals. Remember, it’s your journey, so make the holidays work for you. Here’s to a balanced, joyful season and a bright, strong year ahead!

Whether you’re toasting to loved ones, health, Christmas, or simply to living another year, the holidays allow for a special season of celebration. While it’s great to celebrate, it may seem intimidating to harness your health progress amidst the wining and dining. This doesn’t mean you need to remove yourself from the fun with friends and family, though. We’ve concocted some delicious drink ideas for you to enjoy throughout the holidays and all-year long.

Cranberry Orange Mocktail

Ingredients

  • ¼ cup fresh cranberries
  • ½ in piece of fresh ginger thinly sliced
  • 2 oz pure or 100% cranberry juice
  • 1 can orange flavored sparkling water or seltzer
  • 4 orange slices
  • 2 rosemary sprigs
  • Ice

Preparation

  1. Soak ½ of the fresh cranberries in hot water for about 10 minutes.
  2. Drain water from the cranberries. Divide the softened cranberries and ginger slices in half and add to the bottom of 2 low ball or rocks glasses. Muddle with a wooden spoon or a muddler.
  3. Squeeze 1 orange slice over cranberries and ginger in each glass and muddle some more.
  4. Fill the glass with ice. Pour the 1 ounce of cranberry juice in each glass and ½ of the orange sparkling water or seltzer and stir well.
  5. Remove some leaves from the end of rosemary sprigs and thread the fresh cranberries onto the sprig for garnish. Lay on top or in the glass.
  6. Add an orange slice to the glass for garnish.

Ginger Turmeric Shots

Ingredients

  • 4 inch fresh ginger root peeled and grated
  • 4 inch fresh turmeric root peeled and grated or 1 tbsp ground turmeric powder
  • 2 lemons juiced
  • 1 cup fresh orange juice
  • 4 tbsp raw honey

Preparation

  1. Put the grated ginger and turmeric, or just ginger if using ground turmeric powder, into a paper towel or cheesecloth and squeeze liquid into a large glass with a lid (if using ground turmeric, add it directly to the glass).
  2. Add lemon juice, orange juice, and honey to the glass and shake well.
  3. Divide evenly in 4 small jars with lids. Seal tightly.
Don't feel bummed out by calorie-dense beverages. Instead, try out these merry mocktails to feel your best this Christmas.
Don’t feel bummed out by calorie-dense beverages. Instead, try out these merry mocktails to feel your best this Christmas.

Cucumber Mint Cooler

Ingredients:

  • 1/2 cucumber, thinly sliced
  • 4-5 fresh mint leaves
  • 1/2 lime, juiced
  • 1 cup sparkling water
  • Ice cubes
  • Optional: Stevia or monk fruit sweetener to taste

Instructions:

  1. Muddle the cucumber slices and mint leaves in a glass.
  2. Add lime juice and sweetener if desired.
  3. Fill the glass with ice and top with sparkling water.
  4. Stir gently and garnish with a cucumber slice and mint sprig.

Pomegranate Ginger Spritz

Ingredients:

  • 2 tbsp pomegranate juice
  • 1/2 tsp freshly grated ginger
  • 1 cup sparkling water
  • Ice cubes
  • Pomegranate seeds and a lime wedge for garnish

Instructions:

  1. In a glass, combine pomegranate juice and grated ginger.
  2. Add ice cubes and pour in sparkling water.
  3. Stir gently and garnish with pomegranate seeds and a lime wedge.

Tropical Pineapple Refresher

Ingredients:

  • 1/4 cup unsweetened pineapple juice
  • 1/4 cup coconut water
  • 1/2 lime, juiced
  • 1 cup sparkling water
  • Ice cubes
  • Pineapple slice for garnish

Instructions:

  1. Mix pineapple juice, coconut water, and lime juice in a shaker or glass.
  2. Pour over ice in a serving glass.
  3. Top with sparkling water and garnish with mint or a pineapple slice.

Cheers to You

As you quench your thirst with these tasty tries, be proud of yourself for loving you and your body enough to opt for a healthier option. Your tomorrow morning self will thank you. For more health inspo, check out our socials found at ShedRx.com.

Sign up to meet with a ShedRx healthcare provider today and begin working on a healthier you.

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